Switching between different backend systems to access data is a familiar requirement, but it can seriously hinder performance if done on the fly.

在不同后端系统之间切换以便访问访问是一项熟悉的需求，但它如果采用动态方式则会严重影响性能。

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And the problem seriously hinder the coherent function of system for reducing, it can not play effectively and achieve penalty benefits in the practice.

这些弊端严重阻碍了减刑制度本身功能的发挥，不能充分发挥其实效，实现刑罚的效益。

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Psychological obstacles in writing of middle school students seriously hinder the improvement of writing levels of middle school students and the composition teaching.

中学生中存在的写作心理障碍严重阻碍着中学写作水平的提高和写作教学的顺利进行。

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Dr. Amy Evans, a pediatrician and medical director of the Center for Breastfeeding Medicine in Fresno, California, says that as many as 5% of all women have underlying medical conditions that prevent or seriously hinder lactation: hypoplasia, thyroid problems, hormonal imbalances and insufficient glandular tissue, among others.

CNN: Is the medical community failing breast-feeding moms?